Cancer and Aging Handbook: Research and Practice

A state of the art, multidisciplinary method of melanoma and aging

With the vast majority of cancers taking place in contributors over the age of sixty five opposed to a backdrop of an increasing getting older inhabitants, there's an pressing have to combine the parts of medical oncology and geriatric care. This well timed paintings tackles those matters head-on, proposing a really multidisciplinary and foreign viewpoint on melanoma and getting older from world-renowned specialists in geriatrics, oncology, behavioral technological know-how, psychology, gerontology, and public health.

Unlike different books on geriatric oncology that attention in general on therapy, melanoma and getting older instruction manual: examine and perform examines all stages of the melanoma care continuum, from prevention via evidence-based analysis and therapy to end-of-life care. special medical and learn details is helping consultant readers on potent sufferer care in addition to caregiver education, learn, and intervention. assurance includes:

Epidemiology of melanoma in older adults, plus the original actual, psychological, and social matters involved
Strategies and instructions for prevention, screening, and therapy of older people with cancer
The most typical cancers within the aged, together with breast, colorectal, lung, prostate, and ovarian cancer
Cancer survivorship in older adults in addition to the all-critical problems with palliative care and soreness management
Emerging issues corresponding to caregiver and kin concerns, various versions of care, and value considerations
An crucial source for clinicians and caregivers in addition to researchers drawn to this evolving box, melanoma and getting older guide can also be valuable for public overall healthiness pros and policymakers who have to formulate companies and allocate assets for the starting to be inhabitants of older melanoma sufferers.

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88(5):593–602. 101. Ferbeyre G, de Stanchina E, Querido E, Baptiste N, Prives C, Lowe SW. PML is induced by oncogenic ras and promotes premature senescence. Genes Devel 2000;14(16):2015–2027. 102. Pearson M, Carbone R, Sebastiani C, et al. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature 2000;406(6792):207–210. 103. Ben-Porath I, Weinberg RA. When cells get stressed: An integrative view of cellular senescence.

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