Breast Cancer Management and Molecular Medicine by Martine J. Piccart, William C. Wood, Chie-Mien Hung,

By Martine J. Piccart, William C. Wood, Chie-Mien Hung, Lawrence J. Solin, Fatima Cardoso

Molecular-based drugs is taking middle degree end result of the expanding wisdom of breast melanoma molecular biology. therapy tailoring isn't any longer a dream for the longer term, however the major aim of present research.

This e-book offers an summary of the latest concepts, brokers and methods for breast melanoma that give a contribution to the individualization of therapy. present biomedical study makes a speciality of facilitating the move of molecular biology wisdom into the scientific administration of sufferers, resulting in elevated survival in addition to more suitable caliber of existence. specific cognizance is given during this e-book to organ-specific adapted methods, particular populations, sufferers’ personal tastes and rehabilitation. additionally mentioned intensive are the respective roles of pharmacotherapeutics modelling, useful imaging, molecular staging, genomics and proteomics and their impression at the "re-classification" of breast melanoma, in addition to the medical functions of simple technological know-how. The an important factor of the way to optimally combine organic markers, new applied sciences and new diagnostic and healing techniques into medical trials and medical perform is addressed.

Combining the contributions from authors who're renowned specialists in those fields with editorial reviews, this publication offers an outline of the newest achievements in breast melanoma and their use in medical practice.

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Example text

Drugs . . . . . . . . . . . . . . . . . . . . Environmental Factors . . . . . . . . . . . . Other Risk Factors . . . . . . . . . . . . . . Genetics . . . . . . . . . . . . . . . . . . BRCA1 and BRCA2 . . . . . . . . . . . . . Other Alterations . . . . . . . . . . . . . . Diagnosis . . . . . . . . . . . . . . . . . . Clinical Presentations . . . . . . . . . . . . Mammographic Features .

Long-Term Effects of ERT/HRT . . . . . . . . Osteoporosis . . . . . . . . . . . . . . . . Cardiovascular Disease . . . . . . . . . . . . Alzheimer’s Disease and Cognitive Function . . Colon Cancer . . . . . . . . . . . . . . . . Ovarian Cancer . . . . . . . . . . . . . . . Breast Cancer . . . . . . . . . . . . . . . . 5 Thromboembolic Events . . . . . . . . . . . The Use of ERT/HRT in Women with a Previous Diagnosis of Breast Cancer .

999 Closing Remarks . . . . . . . . . . . . . . 7 ....... 4 Clinical Trials in the Era of Treatment Tailoring . . . . . . . . . . . . . . . . . Introduction . . . . . . . . . . . . . . . . Factors Influencing Treatment Tailoring for Breast Cancer . . . . . . . . . . . . . . Models of Clinical Trials Based on the Concept of Tailored Investigations . . . . . . . . . . Subgroup of Patients with Specific Clinical Features .

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