Advances in Cancer Research, Vol. 13 by George Klein, Sidney Weinhouse, Alexander Haddow (Eds.)

By George Klein, Sidney Weinhouse, Alexander Haddow (Eds.)

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Random chance will ensure t ha t a few immunoblasts will enter the graft and start to react with the foreign cells. Waksman (1968) has suggested that the reaction of lymphoid cells with their target antigen can produce toxic by-products (cf. , 1969) which can damage “innocent bystander” cells that are not otherwise involved in the reaction. It seems feasible t ha t toxic by-products of this nature might somehow encourage the formatiton of a mononuclear cell exudate. I n fact a whole cascade of short-lived pharmacologically active 16 P.

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